Which statement best describes medication-assisted treatment (MAT) for opioid use disorder?

• A. MAT combines medications with counseling to improve outcomes.
• B. MAT is only therapy with no medications.
• C. MAT is for cocaine use disorder only.
• D. MAT is a historical approach no longer used.

Answer: (A)

Medication-assisted treatment for opioid use disorder combines medicines that ease withdrawal and cravings with counseling and other supports to help people change behaviors and improve functioning. The medications—such as methadone, buprenorphine, and naltrexone—address the physical aspects of dependence, stabilizing brain chemistry and reducing urge to use opioids. When these medications are paired with therapy, case management, and psychosocial support, individuals are more likely to stay in treatment, reduce or stop illicit opioid use, and lower the risk of overdose. This integrated approach is why describing MAT as combining medications with counseling is the best fit. It’s not just therapy without medications, it isn’t limited to cocaine use disorder, and it remains a current, recommended practice rather than a historical one.